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Anti-BNIP3L Antibody (1F355)
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Catalog No. TMAB-03180
Anti-BNIP3L Antibody (1F355) is a Rabbit antibody targeting BNIP3L. Anti-BNIP3L Antibody (1F355) can be used in IHC-P,IHC-Fr,IF.
Anti-BNIP3L Antibody (1F355)
Anti-BNIP3L Antibody (1F355)
😃Good
Catalog No. TMAB-03180
Anti-BNIP3L Antibody (1F355) is a Rabbit antibody targeting BNIP3L. Anti-BNIP3L Antibody (1F355) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-BNIP3L Antibody (1F355) is a Rabbit antibody targeting BNIP3L. Anti-BNIP3L Antibody (1F355) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 1F355 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus envelope. Endoplasmic reticulum. Mitochondrion outer membrane. Membrane; Single-pass membrane protein (Potential). Note=Colocalizes with SPATA18 at the mitochondrion outer membrane. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. |
| Immunogen | A synthesized peptide: human BNIP3L |
| Antigen Species | Human |
| Gene Name | BNIP3L |
| Gene ID | |
| Protein Name | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like |
| Uniprot ID | |
| Function | Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor. |
| Molecular Weight | Theoretical: 24 kDa. Actual: 35 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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