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ACVR2B Protein, Human/Cynomolgus, Recombinant (mFc)
(Synonyms: ACVR2B, ActRIIB, Activin RIIB, Activin receptor type-2B) Copy Product InfoSynonyms: ACVR2B, ActRIIB, Activin RIIB, Activin receptor type-2B
Catalog No. TMPK-01585 Copy Product Info
ACVR2B Protein, Human/Cynomolgus, Recombinant (mFc) is expressed in HEK293 Cells. The accession number is Q13705-1(Human)/XP_045242398.1(Cynomolgus).
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $41 | 7-10 days | 7-10 days | |
| 10 µg | $60 | 7-10 days | 7-10 days | |
| 20 µg | $90 | 7-10 days | 7-10 days | |
| 50 µg | $158 | 7-10 days | 7-10 days | |
| 100 µg | $247 | 7-10 days | 7-10 days | |
| 200 µg | $389 | 7-10 days | 7-10 days | |
| 500 µg | $716 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human Activin A, No Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human/Cynomolgus Activin RIIB, mFc Tag with the EC50 of 41.4 ng/ml determined by ELISA (QC Test). |
| Description | ACVR2B Protein, Human/Cynomolgus, Recombinant (mFc) is expressed in HEK293 Cells. The accession number is Q13705-1(Human)/XP_045242398.1(Cynomolgus). |
| Species | Human/Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-mFc |
| Accession Number | Q13705-1(Human)/XP_045242398.1(Cynomolgus) |
| Construction | Ser19-Thr137 (Human)/Ser40-Thr158 (Cynomolgus) |
| Protein Purity | > 95% as determined by Bis-Tris PAGE |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | ACVR2B, ActRIIB, Activin RIIB, Activin receptor type-2B |
| Research Background | ActRIIB (activin receptor type-2B) is an activin receptor subtype constitutively expressed in the whole body, playing a role in cellular proliferation, differentiation, and metabolism. For its various physiological activities, ActRIIB interacts with activin and multiple other ligands including myostatin (MSTN), growth differentiation factor 11 (GDF11), and bone morphogenetic protein 9 (BMP9). |
| Molecular Weight | 39.32 kDa (Predicted); 50-70 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: ACVR2B Protein, Human/Cynomolgus, Recombinant (mFc) chemical structure | ACVR2B Protein, Human/Cynomolgus, Recombinant (mFc) molecular weight
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