AXL Protein, Human, Recombinant (aa 33-442, His)

Name: AXL Protein, Human, Recombinant (aa 33-442, His)
Brand: TargetMol
SKU: TMPY-01601U
Price: 136 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: UFO, Tyro7, JTK11, AXL receptor tyrosine kinase, ARK) Copy Product Info

Synonyms: UFO, Tyro7, JTK11, AXL receptor tyrosine kinase, ARK

Catalog No. TMPY-01601U Copy Product Info

AXL Protein, Human, Recombinant (aa 33-442, His) is expressed in HEK293 Cells. The accession number is NP_068713.2.

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Pack Size	Price	USA Stock	Global Stock
5 µg	Preferential	-	In Stock
10 µg	$32	-	In Stock
20 µg	$47	-	In Stock
50 µg	$84	7-10 days	7-10 days
100 µg	$136	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human AXL, His Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-AXL Antibody, hFc Tag with the EC50 of 10.0 ng/ml determined by ELISA.
Description	AXL Protein, Human, Recombinant (aa 33-442, His) is expressed in HEK293 Cells. The accession number is NP_068713.2.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	NP_068713.2
Construction	Glu33-Ser442
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	UFO, Tyro7, JTK11, AXL receptor tyrosine kinase, ARK
Research Background	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.

Chemical Properties

Molecular Weight

45.4 kDa (Predicted); 65-75 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.