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Anti-CD79b Antibody (2Q682)

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Catalog No. TMAB-04070 Copy Product Info
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Anti-CD79b Antibody (2Q682) is a Rabbit antibody targeting CD79b. Anti-CD79b Antibody (2Q682) can be used in WB,ICC/IF,FCM.
Anti-CD79b Antibody
(2Q682)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CD79b Antibody (2Q682) is a Rabbit antibody targeting CD79b. Anti-CD79b Antibody (2Q682) can be used in WB,ICC/IF,FCM.
Ig Type
IgG
Clone
2Q682
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:100-500; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.
Tissue SpecificityB-cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
A synthesized peptide: human CD79b
Antigen Species
Human
Gene Name
CD79B
Gene ID
Protein Name
B-cell antigen receptor complex-associated protein beta chain
Uniprot ID
Function
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Chemical Properties
Molecular WeightTheoretical: 23 kDa. Actual: 42-50 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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