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Anti-DHFR Antibody (5H593)

😃Good
Catalog No. TMAB-05124

Anti-DHFR Antibody (5H593) is a Rabbit antibody targeting DHFR. Anti-DHFR Antibody (5H593) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.

Anti-DHFR Antibody (5H593)

Anti-DHFR Antibody (5H593)

😃Good
Catalog No. TMAB-05124
Anti-DHFR Antibody (5H593) is a Rabbit antibody targeting DHFR. Anti-DHFR Antibody (5H593) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DHFR Antibody (5H593) is a Rabbit antibody targeting DHFR. Anti-DHFR Antibody (5H593) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
Clone
5H593
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; ICC/IF: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationIsoform Alpha: Mitochondrion membrane; Single-pass membrane protein. Cytoplasm.
Tissue SpecificityWidely expressed in fetal and adult tissues, including throughout the fetal and adult brains and whole blood. Expression is higher in the adult brain than in the fetal brain.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundKey enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2.
Antigen Details
Immunogen
A synthesized peptide: human Dihydrofolate reductase
Antigen Species
Human
Gene Name
DHFR
Gene ID
Protein Name
Dihydrofolate reductase
Uniprot ID
Function
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFRL1.
Chemical Properties
Molecular WeightTheoretical: 21 kDa. Actual: 21 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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