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Anti-TMPRSS2 Antibody (2B63)
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Catalog No. TMAB-13616
Anti-TMPRSS2 Antibody (2B63) is a Rabbit antibody targeting TMPRSS2. Anti-TMPRSS2 Antibody (2B63) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-TMPRSS2 Antibody (2B63)
Anti-TMPRSS2 Antibody (2B63)
Copy Product Info😃Good
Catalog No. TMAB-13616
Anti-TMPRSS2 Antibody (2B63) is a Rabbit antibody targeting TMPRSS2. Anti-TMPRSS2 Antibody (2B63) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-TMPRSS2 Antibody (2B63) is a Rabbit antibody targeting TMPRSS2. Anti-TMPRSS2 Antibody (2B63) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 2B63 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded Human Prostate Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TMPRSS2 Monoclonal Antibody, Unconjugated (TMAB-13616) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 2. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TMPRSS2 Monoclonal Antibody, Unconjugated (TMAB-13616) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining. 3. 25 μg total protein per lane of various lysates (see on figure) probed with TMPRSS2 monoclonal antibody, unconjugated (TMAB-13616) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane and Secreted. Activated by cleavage and secreted. |
| Tissue Specificity | Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Plasma membrane-anchored serine protease that cleaves at arginine residues.Participates in proteolytic cascades of relevance for the normal physiologic function of the prostate.(Microbial infection) Facilitates human coronaviruses SARS-CoV and SARS-CoV-2 infections via two independent mechanisms, proteolytic cleavage of ACE2 receptor which promotes viral uptake, and cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. |
| Immunogen | A synthesized peptide: human TMPRSS2 |
| Antigen Species | Human |
| Gene Name | TMPRSS2 |
| Gene ID | |
| Protein Name | Transmembrane protease serine 2 |
| Uniprot ID | |
| Function | Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland. |
| Molecular Weight | Theoretical: 54 kDa. Actual: 54 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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