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Anti-Profilin 1 Antibody (8Q191)
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Catalog No. TMAB-11769
Anti-Profilin 1 Antibody (8Q191) is a Rabbit antibody targeting Profilin 1. Anti-Profilin 1 Antibody (8Q191) can be used in IP, WB.
Anti-Profilin 1 Antibody (8Q191)
Anti-Profilin 1 Antibody (8Q191)
😃Good
Catalog No. TMAB-11769
Anti-Profilin 1 Antibody (8Q191) is a Rabbit antibody targeting Profilin 1. Anti-Profilin 1 Antibody (8Q191) can be used in IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Profilin 1 Antibody (8Q191) is a Rabbit antibody targeting Profilin 1. Anti-Profilin 1 Antibody (8Q191) can be used in IP, WB. |
| Ig Type | IgG |
| Clone | 8Q191 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton. |
| Tissue Specificity | Expressed in epididymis (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. |
| Immunogen | A synthesized peptide: human Profilin 1 |
| Antigen Species | Human |
| Gene Name | PFN1 |
| Gene ID | |
| Protein Name | Profilin-1 |
| Uniprot ID | |
| Function | Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR. |
| Molecular Weight | Theoretical: 15 kDa. Actual: 15 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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