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Anti-Profilin 1 Antibody (8Q191)

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Catalog No. TMAB-11769

Anti-Profilin 1 Antibody (8Q191) is a Rabbit antibody targeting Profilin 1. Anti-Profilin 1 Antibody (8Q191) can be used in IP, WB.

Anti-Profilin 1 Antibody (8Q191)

Anti-Profilin 1 Antibody (8Q191)

Copy Product Info
😃Good
Catalog No. TMAB-11769
Anti-Profilin 1 Antibody (8Q191) is a Rabbit antibody targeting Profilin 1. Anti-Profilin 1 Antibody (8Q191) can be used in IP, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Profilin 1 Antibody (8Q191) is a Rabbit antibody targeting Profilin 1. Anti-Profilin 1 Antibody (8Q191) can be used in IP, WB.
Ig Type
IgG
Clone
8Q191
Reactivity
Human,Mouse,Rat
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with Profilin 1 monoclonal antibody, unconjugated (TMAB-11769) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
IP=1:20-50; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytoskeleton.
Tissue SpecificityExpressed in epididymis (at protein level).
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundBinds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
Antigen Details
Immunogen
A synthesized peptide: human Profilin 1
Antigen Species
Human
Gene Name
PFN1
Gene ID
Protein Name
Profilin-1
Uniprot ID
Function
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
Chemical Properties
Molecular WeightTheoretical: 15 kDa. Actual: 15 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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