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Anti-TXNRD2/SELZ Antibody (3V57)

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Catalog No. TMAB-13907

Anti-TXNRD2/SELZ Antibody (3V57) is a Rabbit antibody targeting TXNRD2/SELZ. Anti-TXNRD2/SELZ Antibody (3V57) can be used in IF, IHC-Fr, IHC-P, WB.

Anti-TXNRD2/SELZ Antibody (3V57)

Anti-TXNRD2/SELZ Antibody (3V57)

Copy Product Info
😃Good
Catalog No. TMAB-13907
Anti-TXNRD2/SELZ Antibody (3V57) is a Rabbit antibody targeting TXNRD2/SELZ. Anti-TXNRD2/SELZ Antibody (3V57) can be used in IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TXNRD2/SELZ Antibody (3V57) is a Rabbit antibody targeting TXNRD2/SELZ. Anti-TXNRD2/SELZ Antibody (3V57) can be used in IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
3V57
Reactivity
Human,Mouse,Rat
Verified Activity
1. 25 ug total protein per lane of various lysates (see on figure) probed with TXNRD2/SELZ monoclonal antibody, unconjugated (TMAB-13907) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. Paraformaldehyde-fixed, paraffin embedded Human Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TXNRD2/SELZ Monoclonal Antibody, Unconjugated (TMAB-13907) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Human Kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with TXNRD2/SELZ Monoclonal Antibody, Unconjugated (TMAB-13907) at 1:200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L-HRP and DAB staining.
Application
Recommended Dose
IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion.
Tissue SpecificityHighly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundInvolved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis.Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling.
Antigen Details
Immunogen
A synthesized peptide: human TXNRD2
Antigen Species
Human
Gene Name
TXNRD2
Gene ID
Protein Name
Thioredoxin reductase 2, mitochondrial
Uniprot ID
Function
Maintains thioredoxin in a reduced state. Implicated in the defenses against oxidative stress. May play a role in redox-regulated cell signaling.
Chemical Properties
Molecular WeightTheoretical: 57 kDa. Actual: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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