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Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606)
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Catalog No. TMAB-11238
Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606) is a Rabbit antibody targeting Phospho-RIPK3 (Ser232). Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606) can be used in WB.
Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606)
Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606)
😃Good
Catalog No. TMAB-11238
Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606) is a Rabbit antibody targeting Phospho-RIPK3 (Ser232). Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606) is a Rabbit antibody targeting Phospho-RIPK3 (Ser232). Anti-Phospho-RIPK3 (Ser232) Antibody (3Z606) can be used in WB. |
| Ig Type | IgG |
| Clone | 3Z606 |
| Reactivity | Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Cell membrane. Mitochondrion (Potential). |
| Tissue Specificity | Highly expressed in the pancreas. Detected at lower levels in heart, placenta, lung and kidney. Isoform 3 is significantly increased in colon and lung cancers. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Serine/threonine-protein kinase that activates necroptosis and apoptosis, two parallel forms of cell death.Necroptosis, a programmed cell death process in response to death-inducing TNF-alpha family members, is triggered by RIPK3 following activation by ZBP1. |
| Immunogen | A synthesized peptide: mouse Rip3 around the phosphorylation site of S232 |
| Antigen Species | Mouse |
| Gene Name | RIPK3 |
| Gene ID | |
| Protein Name | Receptor-interacting serine/threonine-protein kinase 3 |
| Uniprot ID | |
| Function | Essential for programmed necrosis in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production. |
| Molecular Weight | Theoretical: 53 kDa. Actual: 50 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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