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Elsilimomab

Name: Elsilimomab
Brand: TargetMol
SKU: T76803
Price: 189 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T76803Cas No. 468715-71-1

Alias B-E8, BE8, Anti-IL-6 MAB B-E8, Anti-Human IL6 Recombinant Antibody

Elsilimomab (B-E8) is a monoclonal antibody targeting interleukin-6 (IL-6), inhibiting DNMT3A mutant clone-induced hematopoietic stromal cell senescence, used in the study of multiple myeloma and renal cell carcinoma.

Elsilimomab

🥰Excellent

Purity: 98.44% (SEC-HPLC)

Catalog No. T76803Alias B-E8, BE8, Anti-IL-6 MAB B-E8, Anti-Human IL6 Recombinant AntibodyCas No. 468715-71-1

Pack Size	Price	Availability
1 mg	$189	In Stock
5 mg	$629	In Stock
10 mg	$993	In Stock
25 mg	$1,470	In Stock
50 mg	$1,980	In Stock

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Concentration:7.54 mg/mL

Purity:98.44% (SEC-HPLC)

Resource Download

COA SEC-HPLC SDS-PAGE Instruction Manual of Inhibitory Antibody

Product Introduction

Bioactivity

Description	Elsilimomab (B-E8) is a monoclonal antibody targeting interleukin-6 (IL-6), inhibiting DNMT3A mutant clone-induced hematopoietic stromal cell senescence, used in the study of multiple myeloma and renal cell carcinoma.
Targets&IC50	IL-6:1.4 nM
In vitro	Elsilimomab is an anti-interleukin-6 (IL-6) IgG1 monoclonal antibody, with a KD of 22 pmol/L and an IC50 of 1.4 nM.
Synonyms	B-E8, BE8, Anti-IL-6 MAB B-E8, Anti-Human IL6 Recombinant Antibody

Chemical Properties

Cas No.	468715-71-1
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc