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Anti-APLP2 Antibody (7I465)

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Catalog No. TMAB-02751

Anti-APLP2 Antibody (7I465) is a Rabbit antibody targeting APLP2. Anti-APLP2 Antibody (7I465) can be used in FCM, IF, IHC-Fr, IHC-P, WB.

Anti-APLP2 Antibody (7I465)

Anti-APLP2 Antibody (7I465)

Copy Product Info
😃Good
Catalog No. TMAB-02751
Anti-APLP2 Antibody (7I465) is a Rabbit antibody targeting APLP2. Anti-APLP2 Antibody (7I465) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-APLP2 Antibody (7I465) is a Rabbit antibody targeting APLP2. Anti-APLP2 Antibody (7I465) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
7I465
Reactivity
Human,Mouse,Rat
Verified Activity
1. 25 ug total protein per lane of various lysates (see on figure) probed with APLP2 monoclonal antibody, unconjugated (TMAB-02751) at 1: 1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. The SH-SY5Y (H) cells were fixed with 4% PFA (10 min at r. T.) and then permeabilized with 90% ice-cold methanol for 20 min at -20℃, the cells then were incubated in 5% BSA to block non-specific protein-protein interactions (30 min at r. T.), followed by secondary antibody incubation for 40 min at room temperature. Primary Antibody (green): Rabbit Anti-APLP2 antibody (TMAB-02751, 1: 100); Isotype Control (orange): Rabbit IgG. Blank control (black): PBS. Acquisition of 20,000 events was performed.
Application
Recommended Dose
FCM=1:50-100; IF=1:100-200; IHC-Fr=1:100-200; IHC-P=1:100-200; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Nucleus.
Tissue SpecificityExpressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMay play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.
Antigen Details
Immunogen
A synthesized peptide: human APLP2
Antigen Species
Human
Gene Name
APLP2
Gene ID
Protein Name
Amyloid-like protein 2
Uniprot ID
Function
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Chemical Properties
Molecular WeightTheoretical: 87 kDa. Actual: 87-140 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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