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Anti-GDNF Antibody (2K821)

Catalog No. TMAB-06414 Copy Product Info
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Anti-GDNF Antibody (2K821) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (2K821) can be used in WB,FCM.

Anti-GDNF Antibody (2K821)

Copy Product Info
🥰Excellent
Catalog No. TMAB-06414

Anti-GDNF Antibody (2K821) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (2K821) can be used in WB,FCM.

Anti-GDNF Antibody
(2K821)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GDNF Antibody (2K821) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (2K821) can be used in WB,FCM.
Ig Type
IgG
Clone
2K821
Reactivity
Human,Rat (predicted:Mouse)
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with GDNF monoclonal antibody, unconjugated (TMAB-06414) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityIn the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundNeurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
Antigen Details
Immunogen
A synthesized peptide: human GDNF
Antigen Species
Human
Gene Name
GDNF
Gene ID
Protein Name
Glial cell line-derived neurotrophic factor
Uniprot ID
Function
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
Chemical Properties
Molecular WeightTheoretical: 24 kDa. Actual: 24 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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