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Synonyms: SCYA11, chemokine (C-C motif) ligand 11


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $96 | 7-10 days | 7-10 days | |
| 20 µg | $157 | 7-10 days | 7-10 days | |
| 50 µg | $306 | 7-10 days | 7-10 days | |
| 100 µg | $535 | 7-10 days | 7-10 days | |
| 200 µg | $938 | 7-10 days | 7-10 days | |
| 500 µg | $1,990 | 7-10 days | 7-10 days | |
| 1 mg | $3,520 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | Eotaxin/CCL11 Protein, Human, Recombinant (His) V2 is expressed in E. coli. The accession number is P51671. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-His |
| Accession Number | P51671 |
| Construction | Gly24-Pro97 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM PB, 500mM NaCl, 200 mM L-arginine (pH 7.4). |
| Synonyms | SCYA11, chemokine (C-C motif) ligand 11 |
| Research Background | The chemokine CCL11 (also known as eotaxin-1) is a potent eosinophil chemoattractant that mediates allergic diseases such as asthma, atopic dermatitis, and inflammatory bowel diseases. CCL11 released from activated astrocytes triggers oxidative stress via microglial NOX1 activation and potentiates glutamate-mediated neurotoxicity, which may be involved in the pathogenesis of various neurological disorders. |
| Molecular Weight | 9.46 kDa (Predicted). The protein migrates to 13-15 kDa (reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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