Immobilized Human/Murine/Rat BDNF, No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human TrkB, His Tag with the EC50 of 50.5 ng/ml determined by ELISA.

TrkB Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH31835.

Human

HEK293 Cells

trk-B,TRKB,Tkrb,neurotrophic tyrosine kinase, receptor, type 2,GP145-TrkB/GP95-TrkB,GP145-TrkB

Cys32-His430

> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC

Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Neuron differentiation is likely regulated by a combination of transcription and growth factors. Embryonically, most geniculate neuron development is regulated by the growth factor brain derived neurotrophic factor (BDNF). BDNF expression becomes restricted to subpopulations of taste receptor cells with specific functions,the receptor for BDNF, tropomyosin kinase B receptor (TrkB), may also become developmentally restricted to a subset of taste neurons and could be one factor that is differentially expressed across taste neuron subsets.