TrkB Protein, Human, Recombinant (His) V2

Catalog No. TMPY-00751U

TrkB Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH31835.

TrkB Protein, Human, Recombinant (His) V2

Catalog No. TMPY-00751U

TrkB Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH31835.

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Product Information

Biological Activity	Immobilized Human/Murine/Rat BDNF, No Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human TrkB, His Tag with the EC50 of 50.5 ng/ml determined by ELISA.
Description	TrkB Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is AAH31835.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	AAH31835
Synonyms	trk-B,TRKB,Tkrb,neurotrophic tyrosine kinase, receptor, type 2,GP145-TrkB/GP95-TrkB,GP145-TrkB
Construction	Cys32-His430
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	45.2 kDa (Predicted); 65-80 kDa (Due to glycosylation)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Neuron differentiation is likely regulated by a combination of transcription and growth factors. Embryonically, most geniculate neuron development is regulated by the growth factor brain derived neurotrophic factor (BDNF). BDNF expression becomes restricted to subpopulations of taste receptor cells with specific functions,the receptor for BDNF, tropomyosin kinase B receptor (TrkB), may also become developmentally restricted to a subset of taste neurons and could be one factor that is differentially expressed across taste neuron subsets.