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Anti-CD4 Antibody (6H844)

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Catalog No. TMAB-03982

Anti-CD4 Antibody (6H844) is a Rabbit antibody targeting CD4. Anti-CD4 Antibody (6H844) can be used in IF, IHC-Fr, IHC-P, WB.

Anti-CD4 Antibody (6H844)

Anti-CD4 Antibody (6H844)

😃Good
Catalog No. TMAB-03982
Anti-CD4 Antibody (6H844) is a Rabbit antibody targeting CD4. Anti-CD4 Antibody (6H844) can be used in IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CD4 Antibody (6H844) is a Rabbit antibody targeting CD4. Anti-CD4 Antibody (6H844) can be used in IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
6H844
Reactivity
Mouse
Application
IF
IHC-Fr
IHC-P
WB
Recommended Dose
IF=1:200-500; IHC-Fr=1:200-500; IHC-P=1:200-500; WB=1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Single-pass type I membrane protein. Note=Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
ConstructionRecombinant Antibody
PurificationProtein A purified
FormulationPBS with 0.02% Proclin300,100 μg/ml BSA and 50% glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse CD4
Antigen Species
Mouse
Gene Name
CD4
Gene ID
12504
Protein Name
T-cell surface glycoprotein CD4
Uniprot ID
P06332
Function
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
Chemical Properties
Molecular WeightTheoretical: 51 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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