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Dezamizumab

😃Good
Catalog No. T77391Cas No. 1662664-56-3
Alias GSK2398852, GSK 2398852, Anti-Serum Amyloid P/SAP Reference Antibody (Dezamizumab)

Dezamizumab (GSK 2398852) is a fully humanized recombinant monoclonal immunoglobulin G1 (IgG1) antibody specifically targeting the serum amyloid P component (SAP), a protein universally found in all types of amyloid deposits, and it possesses potential anti-amyloid activity by triggering an immunotherapeutic mechanism for the clearance of amyloid fibrils through macrophage-mediated phagocytosis, which can be applied in the research of amyloid light-chain (AL) amyloidosis and other systemic amyloid diseases.

Dezamizumab

Dezamizumab

😃Good
Purity: 95%
Catalog No. T77391Alias GSK2398852, GSK 2398852, Anti-Serum Amyloid P/SAP Reference Antibody (Dezamizumab)Cas No. 1662664-56-3
Dezamizumab (GSK 2398852) is a fully humanized recombinant monoclonal immunoglobulin G1 (IgG1) antibody specifically targeting the serum amyloid P component (SAP), a protein universally found in all types of amyloid deposits, and it possesses potential anti-amyloid activity by triggering an immunotherapeutic mechanism for the clearance of amyloid fibrils through macrophage-mediated phagocytosis, which can be applied in the research of amyloid light-chain (AL) amyloidosis and other systemic amyloid diseases.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$328-In Stock
5 mg$993-In Stock
10 mg$1,570-In Stock
25 mg$2,330-In Stock
50 mg$3,130-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information

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Purity:98.2% (SDS-PAGE); 98.7% (SEC-HPLC)
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Product Introduction

Bioactivity
Description
Dezamizumab (GSK 2398852) is a fully humanized recombinant monoclonal immunoglobulin G1 (IgG1) antibody specifically targeting the serum amyloid P component (SAP), a protein universally found in all types of amyloid deposits, and it possesses potential anti-amyloid activity by triggering an immunotherapeutic mechanism for the clearance of amyloid fibrils through macrophage-mediated phagocytosis, which can be applied in the research of amyloid light-chain (AL) amyloidosis and other systemic amyloid diseases.
SynonymsGSK2398852, GSK 2398852, Anti-Serum Amyloid P/SAP Reference Antibody (Dezamizumab)
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetSerum Amyloid P/SAP
Chemical Properties
Molecular Weight145.82 kDa
Cas No.1662664-56-3
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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