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Anti-CARD11 Antibody (9H360)
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Catalog No. TMAB-03623
Anti-CARD11 Antibody (9H360) is a Rabbit antibody targeting CARD11. Anti-CARD11 Antibody (9H360) can be used in WB,ICC/IF,FCM.
Anti-CARD11 Antibody (9H360)
Anti-CARD11 Antibody (9H360)
😃Good
Catalog No. TMAB-03623
Anti-CARD11 Antibody (9H360) is a Rabbit antibody targeting CARD11. Anti-CARD11 Antibody (9H360) can be used in WB,ICC/IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CARD11 Antibody (9H360) is a Rabbit antibody targeting CARD11. Anti-CARD11 Antibody (9H360) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Clone | 9H360 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. |
| Tissue Specificity | Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLaS3, MOLT-4, A-549 and G431 cells. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Adapter protein that plays a key role in adaptive immune response by transducing the activation of NF-kappa-B downstream of T-cell receptor (TCR) and B-cell receptor (BCR) engagement.Transduces signals downstream TCR or BCR activation via the formation of a multiprotein complex together with BCL10 and MALT1 that induces NF-kappa-B and MAP kinase p38. |
| Immunogen | A synthesized peptide: human CARD11 |
| Antigen Species | Human |
| Gene Name | CARD11 |
| Gene ID | |
| Protein Name | Caspase recruitment domain-containing protein 11 |
| Uniprot ID | |
| Function | Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. |
| Molecular Weight | Theoretical: 133 kDa. Actual: 133 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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