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Synonyms: SMDF, Pro-NRG1, Pro-NRG 1, Pro-neuregulin-1, membrane-bound isoform, NRG1-IT2, NRG1-beta 1, NRG1 β1, NRG1 α, NRG1, NRG 1, neuregulin 1, Neuregulin 1, neuregulin, NDF, MSTP-131, MSTP131, MSTP 131, MST-131, MST131, MST 131, membrane-bound isoform, HRGA, HRG-1, HRG1, HRG 1, HRG, HGL, Heregulin beta-1, GGF-2, GGF2, GGF 2, GGF, ARIA


| Bioactivity | Immobilized Human Her4, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 0.65 μg/ml determined by ELISA. |
| Description | NRG1 beta 1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 Cells. The accession number is Q02297-6. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | N-hFc (IgG1) |
| Accession Number | Q02297-6 |
| Construction | Ser2-Lys246 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | SMDF, Pro-NRG1, Pro-NRG 1, Pro-neuregulin-1, membrane-bound isoform, NRG1-IT2, NRG1-beta 1, NRG1 β1, NRG1 α, NRG1, NRG 1, neuregulin 1, Neuregulin 1, neuregulin, NDF, MSTP-131, MSTP131, MSTP 131, MST-131, MST131, MST 131, membrane-bound isoform, HRGA, HRG-1, HRG1, HRG 1, HRG, HGL, Heregulin beta-1, GGF-2, GGF2, GGF 2, GGF, ARIA |
| Research Background |
| Molecular Weight | 54.00 kDa (Predicted); 75-90 kDa (Reducing condition, due to glycosylation) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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