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Anti-PIAS1/2 Antibody (9N378)
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Catalog No. TMAB-11433
Anti-PIAS1/2 Antibody (9N378) is a Rabbit antibody targeting PIAS1/2. Anti-PIAS1/2 Antibody (9N378) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Anti-PIAS1/2 Antibody (9N378)
Anti-PIAS1/2 Antibody (9N378)
😃Good
Catalog No. TMAB-11433
Anti-PIAS1/2 Antibody (9N378) is a Rabbit antibody targeting PIAS1/2. Anti-PIAS1/2 Antibody (9N378) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PIAS1/2 Antibody (9N378) is a Rabbit antibody targeting PIAS1/2. Anti-PIAS1/2 Antibody (9N378) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM. |
| Ig Type | IgG |
| Clone | 9N378 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; IP: 1:20-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus speckle. Interaction with CSRP2 may induce a partial redistribution along the cytoskeleton. |
| Tissue Specificity | Expressed in numerous tissues with highest level in testis. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. |
| Immunogen | A synthesized peptide: human PIAS1 |
| Antigen Species | Human |
| Gene Name | PIAS1 |
| Gene ID | |
| Protein Name | E3 SUMO-protein ligase PIAS1 |
| Uniprot ID | |
| Function | Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. In vitro, binds A/T-rich DNA. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context. Together with PRMT1, may repress STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. |
| Molecular Weight | Theoretical: 72, 68 kDa. Actual: 76 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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