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Anti-MFN1 Antibody (2T242)
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Catalog No. TMAC-02590
Alias Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog
Anti-MFN1 Antibody (2T242) is a Rabbit antibody targeting MFN1. Anti-MFN1 Antibody (2T242) can be used in WB,IP,FCM.
Anti-MFN1 Antibody (2T242)
Anti-MFN1 Antibody (2T242)
😃Good
Catalog No. TMAC-02590Alias Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog
Anti-MFN1 Antibody (2T242) is a Rabbit antibody targeting MFN1. Anti-MFN1 Antibody (2T242) can be used in WB,IP,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-MFN1 Antibody (2T242) is a Rabbit antibody targeting MFN1. Anti-MFN1 Antibody (2T242) can be used in WB,IP,FCM. |
| Synonyms | Transmembrane GTPase MFN1, Mitofusin-1, MFN 1, Fzo homolog |
| Ig Type | IgG |
| Clone | 2T242 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of Mitofusin 1 on K562 cells lysates using anti-Mitofusin 1 antibody at 1/1,000 dilution. 2. Flow cytometric analysis of 293 cells with Mitofusin 1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Mitofusin 1 (Mfn1) and mitofusin 2 (Mfn2) are homologs for the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins and are mediators of mitochondrial fusion. A GTPase domain is required for Mfn protein function but the molecular mechanisms of the GTPase-dependent reaction as well as the functional division of the two Mfn proteins are unknown. They are essential for embryonic development and may play a role in the pathobiology of obesity. Although the Mfn1 and Mfn2 genes are broadly expressed, they show different levels of expression in different tissues. Two Mfn1 transcripts are elevated in heart, while Mfn2 mRNA is abundantly expressed in heart and muscle tissue but present only at low levels in many other tissues. Mfn1 localizes to mitochondria and participates in at least two different high molecular weight protein complexes in a GTP-dependent manner. Purified recombinant Mfn1 exhibited approximately eightfold higher GTPase activity than Mfn2. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 84 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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