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Berahyaluronidase alfa
(Synonyms: ALT-B4) Copy Product Info
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Synonyms: ALT-B4
Catalog No. T9901A-1734 Copy Product Info
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Berahyaluronidase alfa is a recombinant human hyaluronidase that temporarily increases tissue permeability by degrading hyaluronan in the extracellular matrix, thereby facilitating the absorption and dispersion of co-administered subcutaneous drugs like pembrolizumab.
Berahyaluronidase alfa
Cas No. 2636716-20-4
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $513 | - | In Stock | |
| 5 mg | $1,530 | - | In Stock | |
| 10 mg | $2,430 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:95.7% (SDS-PAGE); 98.8% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction
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| Description | Berahyaluronidase alfa is a recombinant human hyaluronidase that temporarily increases tissue permeability by degrading hyaluronan in the extracellular matrix, thereby facilitating the absorption and dispersion of co-administered subcutaneous drugs like pembrolizumab. |
| In vitro | In biochemical assays, Berahyaluronidase alfa acts as a spreading factor by catalyzing the hydrolysis of the beta-1,4-glycosidic bonds in hyaluronan. This enzymatic digestion results in a transient decrease in the viscosity of the interstitial ground substance, thereby lowering the resistance to the flow of injected therapeutic fluids [1]. |
| Synonyms | ALT-B4 |
| Application | Functional assay |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Cas No. | 2636716-20-4 |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Berahyaluronidase alfa in vitro
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