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Anti-CD39L4 Antibody (2I566)
😃Good
Catalog No. TMAB-03972
Anti-CD39L4 Antibody (2I566) is a Rabbit antibody targeting CD39L4. Anti-CD39L4 Antibody (2I566) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Anti-CD39L4 Antibody (2I566)
Anti-CD39L4 Antibody (2I566)
😃Good
Catalog No. TMAB-03972
Anti-CD39L4 Antibody (2I566) is a Rabbit antibody targeting CD39L4. Anti-CD39L4 Antibody (2I566) can be used in WB,IHC-P,IHC-Fr,IP,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CD39L4 Antibody (2I566) is a Rabbit antibody targeting CD39L4. Anti-CD39L4 Antibody (2I566) can be used in WB,IHC-P,IHC-Fr,IP,IF. |
| Ig Type | IgG |
| Clone | 2I566 |
| Reactivity | Mouse,Rat (predicted:Human) |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IP: 1:20-50; IF: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane, Single-pass type II membrane protein |
| Tissue Specificity | Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER. |
| Immunogen | A synthesized peptide: human ENTPD5 |
| Antigen Species | Human |
| Gene Name | ENTPD5 |
| Gene ID | |
| Protein Name | Ectonucleoside triphosphate diphosphohydrolase 5 |
| Uniprot ID | |
| Function | Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling |
| Molecular Weight | Theoretical: 48 kDa. Actual: 47 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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