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Anti-CD19 Antibody (7D458) is an antibody targeting CD19. Anti-CD19 Antibody (7D458) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $347 | 7-10 days | 7-10 days |
| Description | Anti-CD19 Antibody (7D458) is an antibody targeting CD19. Anti-CD19 Antibody (7D458) can be used in ELISA. |
| Synonyms | CVID3, CD19 molecule, B4 |
| Ig Type | Rabbit IgG |
| Clone | 7D458 |
| Reactivity | Human |
| Application | |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Membrane raft; Single-pass type I membrane protein. |
| Tissue Specificity | Detected on marginal zone and germinal center B cells in lymph nodes. Detected on blood B cells (at protein level). |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca(2+) stores. Is not required for early steps during B cell differentiation in the blood marrow. Required for normal differentiation of B-1 cells. Required for normal B cell differentiation and proliferation in response to antigen challenges. Required for normal levels of serum immunoglobulins, and for production of high-affinity antibodies in response to antigen challenge. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human CD19 |
| Antigen Species | Human |
| Gene Name | CD19 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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