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Anti-Siglec-8 Antibody (3A714) (Synonyms: Siglec-8, Siglec8, SAF2SAF-2, SAF-2, SAF2, CDw329, CD329 antigen)
Catalog No. TMAH-01088 Copy Product Info
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Anti-Siglec-8 Antibody (3A714) is an antibody targeting Siglec-8. Anti-Siglec-8 Antibody (3A714) can be used in ELISA,IHC.
Anti-Siglec-8 Antibody (3A714)
Copy Product Info🥰Excellent
Catalog No. TMAH-01088
Synonyms Siglec-8, Siglec8, SAF2SAF-2, SAF-2, SAF2, CDw329, CD329 antigen
Anti-Siglec-8 Antibody (3A714) is an antibody targeting Siglec-8. Anti-Siglec-8 Antibody (3A714) can be used in ELISA,IHC.
Anti-Siglec-8 Antibody
(3A714)
(3A714)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Siglec-8 Antibody (3A714) is an antibody targeting Siglec-8. Anti-Siglec-8 Antibody (3A714) can be used in ELISA,IHC. |
| Synonyms | Siglec-8, Siglec8, SAF2SAF-2, SAF-2, SAF2, CDw329, CD329 antigen |
| Ig Type | hIgG1 |
| Clone | 3A714 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-01088 diluted at 1:100 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-human polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Expressed specifically on red blood cells namely basophil, mast cells and eosinophils. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. Preferentially binds to Gal-6-sulfated sialyl-Lewis X glycan epitopes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human SIGLEC8 Protein |
| Antigen Species | Human |
| Gene Name | SIGLEC8 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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