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Anti-GDNF Antibody (7K481)

Catalog No. TMAC-01639 Copy Product Info
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Anti-GDNF Antibody (7K481) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (7K481) can be used in FCM,WB.

Anti-GDNF Antibody (7K481)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01639

Anti-GDNF Antibody (7K481) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (7K481) can be used in FCM,WB.

Anti-GDNF Antibody
(7K481)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GDNF Antibody (7K481) is a Rabbit antibody targeting GDNF. Anti-GDNF Antibody (7K481) can be used in FCM,WB.
Ig Type
IgG
Clone
7K481
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of GDNF on HepG2 cell using anti-GDNF antibody at 1/1,000 dilution.
2. Flow cytometric analysis of SH-SY5Y cells with GDNF antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundGlial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer and is a distantly related member of the TGFβ superfamily of growth regulatory ligands. GDNF contains the seven conserved cysteine residues in the same relative spacing characteristic of all members of the TGFβ superfamily. In embryonic midbrain cultures, GDNF promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. On the basis of these findings, it has been suggested that GDNF may have utility in the treatment of Parkinson's disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 24 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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