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Anti-NUP50 Antibody (5P324)

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Catalog No. TMAB-09709

Anti-NUP50 Antibody (5P324) is a Rabbit antibody targeting NUP50. Anti-NUP50 Antibody (5P324) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.

Anti-NUP50 Antibody (5P324)

Anti-NUP50 Antibody (5P324)

😃Good
Catalog No. TMAB-09709
Anti-NUP50 Antibody (5P324) is a Rabbit antibody targeting NUP50. Anti-NUP50 Antibody (5P324) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-NUP50 Antibody (5P324) is a Rabbit antibody targeting NUP50. Anti-NUP50 Antibody (5P324) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
Clone
5P324
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side (By similarity). Note=Localizes to the nucleoplasmic fibrils of the nuclear pore complex (By similarity).
Tissue SpecificityUbiquitous. Highest levels in testis, peripheral blood leukocytes and fetal liver.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundComponent of the nuclear pore complex that has a direct role in nuclear protein import.Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling.Interacts with regulatory proteins of cell cycle progression including CDKN1B.
Antigen Details
Immunogen
A synthesized peptide: human NUP50
Antigen Species
Human
Gene Name
NUP50
Gene ID
Protein Name
Nuclear pore complex protein Nup50
Uniprot ID
Function
Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with multiple transport receptor proteins including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B.
Chemical Properties
Molecular WeightTheoretical: 50 kDa. Actual: 55 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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