CXCL11 Protein, Human, Recombinant (Active)

Name: CXCL11 Protein, Human, Recombinant (Active)
Brand: TargetMol
SKU: TMPX-00007
Rating: 4.5 (1 reviews)

(Synonyms: Small-inducible cytokine B11, SCYB9B, SCYB11, I-TAC, ITAC, H174, CXCL11, C-X-C motif chemokine 11, Beta-R1) Copy Product Info

Synonyms: Small-inducible cytokine B11, SCYB9B, SCYB11, I-TAC, ITAC, H174, CXCL11, C-X-C motif chemokine 11, Beta-R1

Catalog No. TMPX-00007 Copy Product Info

CXCL11 Protein, Human, Recombinant (Active) is expressed in E. coli. The accession number is O14625.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$86	7-10 days	7-10 days
10 µg	$145	7-10 days	7-10 days
20 µg	$246	7-10 days	7-10 days
50 µg	$422	7-10 days	7-10 days
100 µg	$718	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human IL-2 activated human T-lymphocytes is in a concentration range of 0.1-10 ng/ml.
Description	CXCL11 Protein, Human, Recombinant (Active) is expressed in E. coli. The accession number is O14625.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	O14625
Amino Acid	FPMFKRGRCL CIGPGVKAVK VADIEKASIM YPSNNCDKIE VIITLKENKG QRCLNPKSKQ ARLIIKKVER KNF
Construction	Phe22-Phe94
Protein Purity	> 97% as determined by SDS-PAGE; > 97% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 µm filtered concentrated solution in 20 mM PB, pH 7.4, 100 mM NaCl.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water or aqueous buffer containing 0.1 % BSA. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Small-inducible cytokine B11, SCYB9B, SCYB11, I-TAC, ITAC, H174, CXCL11, C-X-C motif chemokine 11, Beta-R1
Research Background	CXCL11 also known as I-TAC is belonging to the CXC chemokine family and shares 36 % and 37 % amino acid sequence homology with IP-10 and MIG, respectively. It is highly expressed in peripheral blood leukocytes, pancreas and liver. Expression of CXCL11 is strongly induced by IFN-γ and IFN-β, and weakly induced by IFN-α. This chemokine elicits its effects by binding to the cell surface chemokine receptor CXCR3, which with a higher affinity than do the other chemokines for this receptor, CXCL9 and CXCL10. Similar to CXCL10, CXCL11 has been shown to be a chemoattractant for IL-2-activated T-lymphocytes, but not for isolated T-cells, neutrophils or monocytes.

Chemical Properties

Molecular Weight

8.3 kDa (Predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.