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Anti-TRAM2 Antibody (1W462)

Catalog No. TMAB-13725 Copy Product Info
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Anti-TRAM2 Antibody (1W462) is a Rabbit antibody targeting TRAM2. Anti-TRAM2 Antibody (1W462) can be used in WB.

Anti-TRAM2 Antibody (1W462)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13725

Anti-TRAM2 Antibody (1W462) is a Rabbit antibody targeting TRAM2. Anti-TRAM2 Antibody (1W462) can be used in WB.

Anti-TRAM2 Antibody
(1W462)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-TRAM2 Antibody (1W462) is a Rabbit antibody targeting TRAM2. Anti-TRAM2 Antibody (1W462) can be used in WB.
Ig Type
IgG
Clone
1W462
Reactivity
Human,Mouse,Rat
Verified Activity
Western blot analysis of HepG2 cell lysate. Using TRAM2 (TMAB-13725) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundNecessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
Antigen Details
Immunogen
A synthesized peptide: human TRAM2
Antigen Species
Human
Gene Name
TRAM2
Gene ID
Protein Name
Translocating chain-associated membrane protein 2
Uniprot ID
Function
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Chemical Properties
Molecular WeightTheoretical: 43 kDa. Actual: 43 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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