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Anti-TRAM2 Antibody (1W462)

😃Good
Catalog No. TMAB-13725

Anti-TRAM2 Antibody (1W462) is a Rabbit antibody targeting TRAM2. Anti-TRAM2 Antibody (1W462) can be used in WB.

Anti-TRAM2 Antibody (1W462)

Anti-TRAM2 Antibody (1W462)

😃Good
Catalog No. TMAB-13725
Anti-TRAM2 Antibody (1W462) is a Rabbit antibody targeting TRAM2. Anti-TRAM2 Antibody (1W462) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-TRAM2 Antibody (1W462) is a Rabbit antibody targeting TRAM2. Anti-TRAM2 Antibody (1W462) can be used in WB.
Ig Type
IgG
Clone
1W462
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundNecessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
Antigen Details
Immunogen
A synthesized peptide: human TRAM2
Antigen Species
Human
Gene Name
TRAM2
Gene ID
Protein Name
Translocating chain-associated membrane protein 2
Uniprot ID
Function
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding.
Chemical Properties
Molecular WeightTheoretical: 43 kDa. Actual: 43 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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