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Anti-Collagen IV Antibody (6X572)
😃Good
Catalog No. TMAB-04525
Anti-Collagen IV Antibody (6X572) is a Rabbit antibody targeting Collagen IV. Anti-Collagen IV Antibody (6X572) can be used in IHC-P,IHC-Fr,IF.
Anti-Collagen IV Antibody (6X572)
Anti-Collagen IV Antibody (6X572)
😃Good
Catalog No. TMAB-04525
Anti-Collagen IV Antibody (6X572) is a Rabbit antibody targeting Collagen IV. Anti-Collagen IV Antibody (6X572) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Collagen IV Antibody (6X572) is a Rabbit antibody targeting Collagen IV. Anti-Collagen IV Antibody (6X572) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 6X572 |
| Reactivity | Human |
| Application | |
| Recommended Dose | IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix, basement membrane. |
| Tissue Specificity | Highly expressed in placenta. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | PBS (pH7.2) with 40% Glycerol, 0.05% BSA and 0.02% Proclin300. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes the major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Collagen IV |
| Antigen Species | Human |
| Gene Name | COL4A1 |
| Gene ID | |
| Protein Name | Collagen alpha-1(IV) chain |
| Uniprot ID | |
| Function | Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin. |
| Molecular Weight | Theoretical: 161 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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