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Anti-UCHL1 Antibody (2X729) (Synonyms: Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase...)
Catalog No. TMAC-03180 Copy Product Info
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Anti-UCHL1 Antibody (2X729) is a Rabbit antibody targeting UCHL1. Anti-UCHL1 Antibody (2X729) can be used in ICC/IF,IHC,IP,WB.
Anti-UCHL1 Antibody (2X729)
Copy Product Info🥰Excellent
Catalog No. TMAC-03180
Synonyms Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117
Anti-UCHL1 Antibody (2X729) is a Rabbit antibody targeting UCHL1. Anti-UCHL1 Antibody (2X729) can be used in ICC/IF,IHC,IP,WB.
Anti-UCHL1 Antibody
(2X729)
(2X729)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-UCHL1 Antibody (2X729) is a Rabbit antibody targeting UCHL1. Anti-UCHL1 Antibody (2X729) can be used in ICC/IF,IHC,IP,WB. |
| Synonyms | Uch-L1, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), PGP95, PGP9.5, PARK5, NDGOA, HEL-117 |
| Ig Type | IgG |
| Clone | 2X729 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PGP9.5 on A549 cell lysates using anti-PGP9.5 antibody at 1/1,000 dilution. 2. ICC staining PGP9.5 in N2A cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining PGP9.5 in PC-12 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.    |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:100-500; IP: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | UCH-L1 (ubiquitin C-terminal hydrolase) is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCH-L1 is highly specific to neurons and to cells of the diffuse neuroendocrine system and their tumors. UCH-L1 is expressed in brain neurons. Examination of specific brain regions reveals expression in all areas tested, particularly in the substantia nigra. UCH-L1 represents 1-2% of total soluble brain protein. Its occurrence in Lewy bodies and its function in the proteasome pathway make it a compelling candidate gene in Parkinson disease. The gene which encodes UCH-L1 maps to human chromosome 4p13. The 230 amino acid human UCH-L3 protein is 54% identical to that of UCH-L1. UCH-L3 is the predominant thiol protease and has high-affinity binding sites for ubiquitin. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 25 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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