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Anti-CD11b Antibody (3Y731)
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Catalog No. TMAB-03830
Anti-CD11b Antibody (3Y731) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (3Y731) can be used in WB.
Anti-CD11b Antibody (3Y731)
Anti-CD11b Antibody (3Y731)
Copy Product Info😃Good
Catalog No. TMAB-03830
Anti-CD11b Antibody (3Y731) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (3Y731) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD11b Antibody (3Y731) is a Rabbit antibody targeting CD11b. Anti-CD11b Antibody (3Y731) can be used in WB. |
| Ig Type | IgG |
| Clone | 3Y731 |
| Reactivity | Mouse,Rat (predicted:Human) |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with CD11b monoclonal antibody, unconjugated (TMAB-03830) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Predominantly expressed in monocytes and granulocytes. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| Immunogen | A synthesized peptide: human CD11b |
| Gene Name | ITGAM |
| Gene ID | |
| Protein Name | Integrin alpha-M |
| Function | Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. |
| Molecular Weight | Theoretical: 125 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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