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Anti-GABARAPL2 Antibody (4B51)

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Catalog No. TMAB-06248

Anti-GABARAPL2 Antibody (4B51) is a Rabbit antibody targeting GABARAPL2. Anti-GABARAPL2 Antibody (4B51) can be used in WB.

Anti-GABARAPL2 Antibody (4B51)

Anti-GABARAPL2 Antibody (4B51)

😃Good
Catalog No. TMAB-06248
Anti-GABARAPL2 Antibody (4B51) is a Rabbit antibody targeting GABARAPL2. Anti-GABARAPL2 Antibody (4B51) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GABARAPL2 Antibody (4B51) is a Rabbit antibody targeting GABARAPL2. Anti-GABARAPL2 Antibody (4B51) can be used in WB.
Ig Type
IgG
Clone
4B51
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationGolgi apparatus.
Tissue SpecificityUbiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundIn the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing (1). GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC (2,3). In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein) (4-6). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton (6). The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex (6).
Antigen Details
Immunogen
A synthesized peptide: human GABARAPL2
Gene Name
GABARAPL2
Gene ID
Protein Name
gamma-aminobutyric acid receptor-associated protein-like 2
Function
Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
Chemical Properties
Molecular WeightTheoretical: 14 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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