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Cyclophilin A Protein, Human, Recombinant (His) V2
(Synonyms: peptidylprolyl isomerase A (cyclophilin A), HEL-S-69p, CYPH, CYPA) Copy Product InfoSynonyms: peptidylprolyl isomerase A (cyclophilin A), HEL-S-69p, CYPH, CYPA
Catalog No. TMPY-02177U Copy Product Info
Cyclophilin A Protein, Human, Recombinant (His) V2 is expressed in E. coli. The accession number is P62937.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $109 | 7-10 days | 7-10 days | |
| 20 µg | $182 | 7-10 days | 7-10 days | |
| 50 µg | $357 | 7-10 days | 7-10 days | |
| 100 µg | $600 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | Cyclophilin A Protein, Human, Recombinant (His) V2 is expressed in E. coli. The accession number is P62937. |
| Species | Human |
| Expression System | E. coli |
| Tag | C-6xHis |
| Accession Number | P62937 |
| Construction | Val2-Glu165 |
| Protein Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, 1mM DTT, pH 7.4. |
| Synonyms | peptidylprolyl isomerase A (cyclophilin A), HEL-S-69p, CYPH, CYPA |
| Research Background | Cyclophilin A, also known as peptidylprolyl isomerase A (PPIA), is an 18 kDa protein that catalyzes cis-trans isomerization at proline imidic peptide bonds, thereby promoting protein folding/trafficking and regulating protein activity. Cyclophilin A has multiple known functions in inflammation. Intracellularly, cyclophilin A interacts with interleukin (IL)-2 inducible T cell kinase (ITK) to tune T cell receptor signaling. Extracellularly, cyclophilin A is known to function as a leukocyte chemotactic factor. Cells secrete cyclophilin A by a vesicular secretory pathway in response to lipopolysaccharide and oxidative stress, or cyclophilin A may be released during cell death. Cyclophilin A influences inflammatory responses through its actions on immune activation and/or leukocyte trafficking. |
| Molecular Weight | 18.8 kDa (Predicted); 15-20 kDa (Reducing conditions) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: Cyclophilin A Protein, Human, Recombinant (His) V2 chemical structure | Cyclophilin A Protein, Human, Recombinant (His) V2 molecular weight
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