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Anti-SIN3A Antibody (7T227)

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Catalog No. TMAB-12801

Anti-SIN3A Antibody (7T227) is a Rabbit antibody targeting SIN3A. Anti-SIN3A Antibody (7T227) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.

Anti-SIN3A Antibody (7T227)

Anti-SIN3A Antibody (7T227)

😃Good
Catalog No. TMAB-12801
Anti-SIN3A Antibody (7T227) is a Rabbit antibody targeting SIN3A. Anti-SIN3A Antibody (7T227) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SIN3A Antibody (7T227) is a Rabbit antibody targeting SIN3A. Anti-SIN3A Antibody (7T227) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
7T227
Reactivity
Human,Mouse
Application
FCM
ICC/IF
IF
IHC-Fr
IHC-P
WB
Recommended Dose
FCM=1:50-100; ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:50-200; IHC-P=1:50-200; WB=1:1000-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Nucleus, nucleolus. Note=Recruited to the nucleolus by SAP30L (By similarity).
Tissue SpecificityWidely expressed. Highest levels in testis, lung and thymus.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundActs as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation.
Antigen Details
Immunogen
A synthesized peptide: human SIN3A
Antigen Species
Human
Gene Name
SIN3A
Gene ID
25942
Protein Name
Paired amphipathic helix protein Sin3a
Uniprot ID
Q96ST3
Function
Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation.
Chemical Properties
Molecular WeightTheoretical: 145 kDa. Actual: 150 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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