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Anti-DNA Polymerase beta Antibody (8E862) is a Rabbit antibody targeting DNA Polymerase beta. Anti-DNA Polymerase beta Antibody (8E862) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
| Description | Anti-DNA Polymerase beta Antibody (8E862) is a Rabbit antibody targeting DNA Polymerase beta. Anti-DNA Polymerase beta Antibody (8E862) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB. |
| Ig Type | IgG |
| Clone | 8E862 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:100-200; IHC-P=1:100-200; IP=1:20-50; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Monomer. Interacts with APEX1, HUWE1/ARF-BP1, STUB1/CHIP and USP47. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Repair polymerase that plays a key role in base-excision repair. |
| Immunogen | A synthesized peptide: human DNA polymerase beta |
| Antigen Species | Human |
| Gene Name | POLB |
| Gene ID | |
| Protein Name | DNA polymerase beta |
| Uniprot ID | |
| Function | Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. |
| Molecular Weight | Theoretical: 38 kDa. Actual: 38 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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