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Anti-DNA Polymerase beta Antibody (8E862)

😃Good
Catalog No. TMAB-05214

Anti-DNA Polymerase beta Antibody (8E862) is a Rabbit antibody targeting DNA Polymerase beta. Anti-DNA Polymerase beta Antibody (8E862) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.

Anti-DNA Polymerase beta Antibody (8E862)

Anti-DNA Polymerase beta Antibody (8E862)

😃Good
Catalog No. TMAB-05214
Anti-DNA Polymerase beta Antibody (8E862) is a Rabbit antibody targeting DNA Polymerase beta. Anti-DNA Polymerase beta Antibody (8E862) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DNA Polymerase beta Antibody (8E862) is a Rabbit antibody targeting DNA Polymerase beta. Anti-DNA Polymerase beta Antibody (8E862) can be used in ICC/IF, IF, IHC-Fr, IHC-P, IP, WB.
Ig Type
IgG
Clone
8E862
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:100-200; IHC-P=1:100-200; IP=1:20-50; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMonomer. Interacts with APEX1, HUWE1/ARF-BP1, STUB1/CHIP and USP47.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundRepair polymerase that plays a key role in base-excision repair.
Antigen Details
Immunogen
A synthesized peptide: human DNA polymerase beta
Antigen Species
Human
Gene Name
POLB
Gene ID
Protein Name
DNA polymerase beta
Uniprot ID
Function
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
Chemical Properties
Molecular WeightTheoretical: 38 kDa. Actual: 38 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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