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Anti-RheB Antibody (8S39)

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Catalog No. TMAC-03596

Anti-RheB Antibody (8S39) is a Rabbit antibody targeting RheB. Anti-RheB Antibody (8S39) can be used in WB,ICC,IF,IHC,FCM.

Anti-RheB Antibody (8S39)

Anti-RheB Antibody (8S39)

😃Good
Catalog No. TMAC-03596
Anti-RheB Antibody (8S39) is a Rabbit antibody targeting RheB. Anti-RheB Antibody (8S39) can be used in WB,ICC,IF,IHC,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-RheB Antibody (8S39) is a Rabbit antibody targeting RheB. Anti-RheB Antibody (8S39) can be used in WB,ICC,IF,IHC,FCM.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundH-, K- and N-Ras represent the prototype members of a family of small G proteins which are frequently activated to an oncogenic state in a wide variety of human tumors. Activation is due to point mutations at position 12 or 61 within their coding sequence. Such mutations cause these proteins to be constitutively converted to their active GTP-bound rather than the inactive GDP-bound state. The related human R-Ras gene was initially cloned by low stringency hybridization methods. Position 38 or 87 mutants of R-Ras (analogous to positions 12 and 61 in H-Ras) have been shown to be capable of activating oncogenic function. Ras p21 in its active GTP binding state binds to Raf-1, resulting in activation of the MAP kinase signaling cascade. An additional member of the Ras family, Rheb (Ras-related GTP-binding protein), also interacts with Raf-1. This interaction is potentiated by growth factors and agents that increase cAMP levels.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human RHEB aa 1-250
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 20 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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