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Anti-RheB Antibody (8S39)

(Synonyms: RHEB2, Ras homolog enriched in brain) Copy Product Info
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Synonyms: RHEB2, Ras homolog enriched in brain

Catalog No. TMAC-03596 Copy Product Info
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Anti-RheB Antibody (8S39) is a Rabbit antibody targeting RheB. Anti-RheB Antibody (8S39) can be used in FCM,ICC,IF,IHC,WB.
Anti-RheB Antibody
(8S39)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-RheB Antibody (8S39) is a Rabbit antibody targeting RheB. Anti-RheB Antibody (8S39) can be used in FCM,ICC,IF,IHC,WB.
SynonymsRHEB2, Ras homolog enriched in brain
Ig Type
IgG
Clone
8S39
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundH-, K- and N-Ras represent the prototype members of a family of small G proteins which are frequently activated to an oncogenic state in a wide variety of human tumors. Activation is due to point mutations at position 12 or 61 within their coding sequence. Such mutations cause these proteins to be constitutively converted to their active GTP-bound rather than the inactive GDP-bound state. The related human R-Ras gene was initially cloned by low stringency hybridization methods. Position 38 or 87 mutants of R-Ras (analogous to positions 12 and 61 in H-Ras) have been shown to be capable of activating oncogenic function. Ras p21 in its active GTP binding state binds to Raf-1, resulting in activation of the MAP kinase signaling cascade. An additional member of the Ras family, Rheb (Ras-related GTP-binding protein), also interacts with Raf-1. This interaction is potentiated by growth factors and agents that increase cAMP levels.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human RHEB aa 1-250
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 20 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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