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Anti-Placental Lactogen Antibody (7C243)

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Catalog No. TMAB-11517

Anti-Placental Lactogen Antibody (7C243) is a Rabbit antibody targeting Placental Lactogen. Anti-Placental Lactogen Antibody (7C243) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Placental Lactogen Antibody (7C243)

Anti-Placental Lactogen Antibody (7C243)

😃Good
Catalog No. TMAB-11517
Anti-Placental Lactogen Antibody (7C243) is a Rabbit antibody targeting Placental Lactogen. Anti-Placental Lactogen Antibody (7C243) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Placental Lactogen Antibody (7C243) is a Rabbit antibody targeting Placental Lactogen. Anti-Placental Lactogen Antibody (7C243) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
7C243
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; IHC-P: 1:200-1000; IHC-Fr: 1:200-1000; IF: 1:200-1000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificityExpressed in placenta, maternal decidua and fetal membranes. Within placenta, expressed in trophoblasts, stromal cells, villous endothelium, syncytiotrophoblast apical membrane and villous stroma. Within fetal membranes, expressed in amnion, chorioamniotic mesenchyma and chorion (at protein level). Expressed in cardiac, smooth, and skeletal muscle, neurons, thymus, kidney and hematopoietic cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPBS, Glycerol, BSA.
Concentration1mg/ml
Research BackgroundPlacental lactogens, also referred to as chorionic somatomammotropin hormones, are protein hormones. They are produced in the mammalian placenta and are similar in structure and function to growth hormones. Together, placental lactogens and growth factors play an essential role to assure successful lactation after pregnancy. Placental lactogens also modify the metabolic state of the mother during pregnancy to supply energy to the fetus. Placental lactogen I is a member of the somatotropin/prolactin family of hormones. The proteins in this family are crucial in mammalian growth control. Placental lactogen I is expressed primarily during mid-pregnancy, and it has been reported that DNA methylation regulates its tissue expression in rats. Placental lactogen II is expressed later in pregnancy and, in mice, its secretion is regulated by the inhibitory control of GH, the concentration of which increases rapidly at the beginning of the last half of pregnancy.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Placental lactogen
Antigen Species
Human
Gene Name
CSH2
Gene ID
Protein Name
Chorionic somatomammotropin hormone 2
Uniprot ID
Function
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
Chemical Properties
Molecular WeightTheoretical: 22 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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