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Anti-LRP/MVP Antibody (7J812)

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Catalog No. TMAB-08394

Anti-LRP/MVP Antibody (7J812) is a Rabbit antibody targeting LRP/MVP. Anti-LRP/MVP Antibody (7J812) can be used in WB,IHC-P,IHC-Fr,IF,FCM.

Anti-LRP/MVP Antibody (7J812)

Anti-LRP/MVP Antibody (7J812)

😃Good
Catalog No. TMAB-08394
Anti-LRP/MVP Antibody (7J812) is a Rabbit antibody targeting LRP/MVP. Anti-LRP/MVP Antibody (7J812) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-LRP/MVP Antibody (7J812) is a Rabbit antibody targeting LRP/MVP. Anti-LRP/MVP Antibody (7J812) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Clone
7J812
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
IHC-Fr
IF
FCM
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus, nuclear pore complex.
Tissue SpecificityPresent in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundRequired for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Antigen Details
Immunogen
A synthesized peptide: human MVP
Antigen Species
Human
Gene Name
MVP
Gene ID
9961
Protein Name
Major vault protein
Uniprot ID
Q14764
Function
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Chemical Properties
Molecular WeightTheoretical: 99 kDa. Actual: 99 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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