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Anti-LRP/MVP Antibody (7J812)

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Catalog No. TMAB-08394 Copy Product Info
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Anti-LRP/MVP Antibody (7J812) is a Rabbit antibody targeting LRP/MVP. Anti-LRP/MVP Antibody (7J812) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Anti-LRP/MVP Antibody
(7J812)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-LRP/MVP Antibody (7J812) is a Rabbit antibody targeting LRP/MVP. Anti-LRP/MVP Antibody (7J812) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Clone
7J812
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus, nuclear pore complex.
Tissue SpecificityPresent in most normal tissues. Higher expression observed in epithelial cells with secretory and excretory functions, as well as in cells chronically exposed to xenobiotics, such as bronchial cells and cells lining the intestine. Overexpressed in many multidrug-resistant cancer cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundRequired for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates IFNG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Antigen Details
Immunogen
A synthesized peptide: human MVP
Antigen Species
Human
Gene Name
MVP
Gene ID
Protein Name
Major vault protein
Uniprot ID
Function
Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.
Chemical Properties
Molecular WeightTheoretical: 99 kDa. Actual: 108 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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