DLL4 Protein, Human, Recombinant (hFc) V2

Name: DLL4 Protein, Human, Recombinant (hFc) V2
Brand: TargetMol
SKU: TMPY-00776U
Rating: 4.5 (1 reviews)

(Synonyms: δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4) Copy Product Info

Synonyms: δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4

Catalog No. TMPY-00776U Copy Product Info

DLL4 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NR61.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$47	7-10 days	7-10 days
10 µg	$74	7-10 days	7-10 days
20 µg	$118	7-10 days	7-10 days
50 µg	$228	7-10 days	7-10 days
100 µg	$405	7-10 days	7-10 days
200 µg	$716	7-10 days	7-10 days
500 µg	$1,520	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human DLL4, hFc Tag at 1 μg/ml (100 μl/Well) on the plate. Dose response curve for Biotinylated Anti-DLL4 Antibody, hFc Tag with the EC50 of 16.5 ng/ml determined by ELISA (QC Test). Human DLL4, hFc Tag captured on CM5 Chip via Protein A can bind Human Notch 1, His Tag with an affinity constant of 0.48 μM as determined in SPR assay (Biacore T200).
Description	DLL4 Protein, Human, Recombinant (hFc) V2 is expressed in HEK293 Cells. The accession number is Q9NR61.
Species	Human
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	Q9NR61
Construction	Ser27-Pro524
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	δ-like 4 (Drosophila), δ-like 4, hδ2, hdelta2, delta-like 4 (Drosophila), Delta-like 4
Research Background	Delta-like protein 4 (DLL4) is a type I membrane protein belonging to the Delta/Serrate/Lag2 (DSL) family of Notch ligands. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate.

Chemical Properties

Molecular Weight

81.1 kDa (Predicted); 82-90 kDa (Due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.