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Anti-LPA1 Antibody (5L652)

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Catalog No. TMAB-08362

Anti-LPA1 Antibody (5L652) is a Rabbit antibody targeting LPA1. Anti-LPA1 Antibody (5L652) can be used in IHC-P,IHC-Fr,IF.

Anti-LPA1 Antibody (5L652)

Anti-LPA1 Antibody (5L652)

😃Good
Catalog No. TMAB-08362
Anti-LPA1 Antibody (5L652) is a Rabbit antibody targeting LPA1. Anti-LPA1 Antibody (5L652) can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-LPA1 Antibody (5L652) is a Rabbit antibody targeting LPA1. Anti-LPA1 Antibody (5L652) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
5L652
Reactivity
Human
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCell surface. Cell membrane; Multi-pass membrane protein. Note=Prior to LPA treatment found predominantly at the cell surface but in the presence of LPA co-localizes with RALA in the endocytic vesicles.
Tissue SpecificityExpressed in many adult organs, including brain, heart, colon, small intestine, placenta, prostate, ovary, pancreas, testes, spleen, skeletal muscle, and kidney. Little or no expression in liver, lung, thymus, or peripheral blood leukocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPlays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G12/G13, and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels.
Antigen Details
Immunogen
A synthesized peptide: human LPA receptor 1
Antigen Species
Human
Gene Name
LPAR1
Gene ID
1902
Protein Name
Lysophosphatidic acid receptor 1
Uniprot ID
Q92633
Function
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.
Chemical Properties
Molecular WeightTheoretical: 41 kDa. Actual: 39 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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