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Etaracizumab

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Catalog No. T76807Cas No. 892553-42-3
Alias MEDI523, MEDI 523, LM609, LM 609, Anti-αvβ3 Integrin Recombinant Antibody

Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.

Etaracizumab

Etaracizumab

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Catalog No. T76807Alias MEDI523, MEDI 523, LM609, LM 609, Anti-αvβ3 Integrin Recombinant AntibodyCas No. 892553-42-3
Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$289In StockIn Stock
5 mg$753In StockIn Stock
10 mg$1,180-In Stock
25 mg$1,780-In Stock
50 mg$2,380-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.32% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.
In vivo
In the SKOV3ip1 model, both Bevacizumab (5 mg/kg twice weekly) and Etaracizumab (10 mg/kg twice weekly) reduced tumor growth by 52-63%, compared with either drug alone. The combination treatment reduced growth by 63-74%.
SynonymsMEDI523, MEDI 523, LM609, LM 609, Anti-αvβ3 Integrin Recombinant Antibody
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIntegrin aVb3
Chemical Properties
Molecular Weight144.64 kDa
Cas No.892553-42-3
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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