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Anti-CD21 Antibody (2Z920)

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Catalog No. TMAC-00680
Alias SLEB9, EBV receptor, CVID7, CR2, CD21, C3DRSLEB9, C3DR

Anti-CD21 Antibody (2Z920) is a Rabbit antibody targeting CD21. Anti-CD21 Antibody (2Z920) can be used in WB,ICC,IHC,IP,FCM.

Anti-CD21 Antibody (2Z920)

Anti-CD21 Antibody (2Z920)

😃Good
Catalog No. TMAC-00680Alias SLEB9, EBV receptor, CVID7, CR2, CD21, C3DRSLEB9, C3DR
Anti-CD21 Antibody (2Z920) is a Rabbit antibody targeting CD21. Anti-CD21 Antibody (2Z920) can be used in WB,ICC,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-CD21 Antibody (2Z920) is a Rabbit antibody targeting CD21. Anti-CD21 Antibody (2Z920) can be used in WB,ICC,IHC,IP,FCM.
SynonymsSLEB9, EBV receptor, CVID7, CR2, CD21, C3DRSLEB9, C3DR
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of CD21 on different lysates using anti-CD21 antibody at 1/1,000 dilution. Positive control: Lane 1: Daudi, Lane 2: Raji.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD21 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD21 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human gastric cancer tissue using anti-CD21 antibody. Counter stained with hematoxylin.
5. ICC staining CD21 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining CD21 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCD21 is a type I integral membrane glycoprotein that serves as a receptor for the C3d complement fragment and for the Epstein-Barr virus. It plays a role in B cell activation and proliferation and undergoes phosphorylation after B cell activation with phorbol esters. CD21 is expressed on mature B cells, follicular dendritic cells, pharyngeal and cervical epithelial cells and a subset of thymocytes. The adaptive immune response is tightly regulated to limit responding cells in an antigen-specific manner. On B cells, co-receptors CD21/CD19 modulate the strength of B cell Ag receptor (BCR) signals, thereby influencing cell fate. Complement receptor (CR) type 2 (CR2/ CD21) is normally expressed during the immature and mature stages of B cell development. In association with CD19, CR21 plays an important role in enhancing mature B cell responses to foreign antigens.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 130-155 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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