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BMP-2 Protein, Human/Mouse/Rat/Rhesus/Canine, Recombinant is expressed in E. coli. The accession number is P12643.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $98 | 7-10 days | 7-10 days | |
| 10 μg | $166 | 7-10 days | 7-10 days | |
| 20 μg | $275 | 7-10 days | 7-10 days | |
| 50 μg | $393 | 7-10 days | 7-10 days | |
| 100 μg | $539 | 7-10 days | 7-10 days | |
| 200 μg | $945 | 7-10 days | 7-10 days | |
| 500 μg | $1,990 | 7-10 days | 7-10 days | |
| 1 mg | $3,520 | 7-10 days | 7-10 days |
| Biological Activity | Measured by its ability to induce Alkaline Phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 40-200 ng/mL (QC Test). |
| Description | BMP-2 Protein, Human/Mouse/Rat/Rhesus/Canine, Recombinant is expressed in E. coli. The accession number is P12643. |
| Species | Human/Rhesus macaque/Mouse/Rat/Canine |
| Expression System | E. coli |
| Accession Number | P12643 |
| Synonyms | bone morphogenetic protein 2 |
| Construction | Gln283-Arg396 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Molecular Weight | 12.90 kDa (Predicted and reducing conditions) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in 100mM Acetic Acid (pH 2.8). Normally 8% trehalose is added as protectant before lyophilization. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Bone morphogenetic protein 2 (BMP2), a member of the transforming growth factor-β (TGF-β) super-family, is one of the main chondrogenic growth factors involved in cartilage regeneration. BMP2 is known to induce chondrogenic differentiation in various types of stem cells in vitro. However, BMP2 also induces osteogenic differentiation and endochondral ossification in mesenchymal stem cells (MSCs). |
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