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Anti-SNX1 Antibody (7Z490)
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Catalog No. TMAC-03817
Alias Vps5, Sorting nexin-1, Sorting nexin 1A, Sorting nexin 1, SNX1A, SNX1_HUMAN, Snx1, SNX 1a, SNX 1, MGC8664, HsT17379
Anti-SNX1 Antibody (7Z490) is a Rabbit antibody targeting SNX1. Anti-SNX1 Antibody (7Z490) can be used in WB,ICC,IF,IHC,FCM.
Anti-SNX1 Antibody (7Z490)
Anti-SNX1 Antibody (7Z490)
😃Good
Catalog No. TMAC-03817Alias Vps5, Sorting nexin-1, Sorting nexin 1A, Sorting nexin 1, SNX1A, SNX1_HUMAN, Snx1, SNX 1a, SNX 1, MGC8664, HsT17379
Anti-SNX1 Antibody (7Z490) is a Rabbit antibody targeting SNX1. Anti-SNX1 Antibody (7Z490) can be used in WB,ICC,IF,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SNX1 Antibody (7Z490) is a Rabbit antibody targeting SNX1. Anti-SNX1 Antibody (7Z490) can be used in WB,ICC,IF,IHC,FCM. |
| Synonyms | Vps5, Sorting nexin-1, Sorting nexin 1A, Sorting nexin 1, SNX1A, SNX1_HUMAN, Snx1, SNX 1a, SNX 1, MGC8664, HsT17379 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of SNX1 on human skin tissue lysate using anti-SNX1 antibody at 1/2,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded rat epididymis tissue using anti-SNX1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-SNX1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human breast cancer tissue using anti-SNX1 antibody. Counter stained with hematoxylin. 5. ICC staining SNX1 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. ICC staining SNX1 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 7. ICC staining SNX1 in SiHa cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 8. Flow cytometric analysis of SiHa cells with SNX1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IHC: 1:50-200; ICC:IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking. SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor. SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain. These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases. These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes. The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human SNX1 aa 50-250 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 63 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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