GRO beta/CXCL2 Protein, Human, Recombinant V2

Name: GRO beta/CXCL2 Protein, Human, Recombinant V2
Brand: TargetMol
SKU: TMPY-00006U
Rating: 4.5 (1 reviews)

(Synonyms: SCYB2, MIP-2a, MIP2A, MIP2, MGSA-b, GROb, GRO2, GRO β/CXCL2, CINC-2a, chemokine (C-X-C motif) ligand 2) Copy Product Info

Synonyms: SCYB2, MIP-2a, MIP2A, MIP2, MGSA-b, GROb, GRO2, GRO β/CXCL2, CINC-2a, chemokine (C-X-C motif) ligand 2

Catalog No. TMPY-00006U Copy Product Info

GRO beta/CXCL2 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P19875.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	7-10 days	7-10 days
10 µg	$165	7-10 days	7-10 days
20 µg	$243	7-10 days	7-10 days
50 µg	$413	7-10 days	7-10 days
100 µg	$618	7-10 days	7-10 days
200 µg	$1,080	7-10 days	7-10 days
500 µg	$2,280	7-10 days	7-10 days
1 mg	$4,020	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	The EC 50 value of human GRO beta on Ca 2+ mobilization assay in CHO-K1/Gα15/hCXCR2 cells (human Gα15 and human CXCR2 stably expressed in CHO-K1 cells) is less than 200.0 ng/ml.
Description	GRO beta/CXCL2 Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is P19875.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P19875
Construction	Ala35-Asn107
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.2 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SCYB2, MIP-2a, MIP2A, MIP2, MGSA-b, GROb, GRO2, GRO β/CXCL2, CINC-2a, chemokine (C-X-C motif) ligand 2
Research Background	Human GRO-α, GRO-β (MIP-2α), and GRO-γ (MIP-2β) are products of three distinct, nonallelichuman genes. GRO-β and GRO-γ share 90% and 86% amino acid sequence homology, respectively, with GROα. All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors.GRO expression is inducible by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively.Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils.

Chemical Properties

Molecular Weight

8 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.