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Anti-Cytokeratin 4 Antibody (1T236)

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Catalog No. TMAB-04955

Anti-Cytokeratin 4 Antibody (1T236) is a Rabbit antibody targeting Cytokeratin 4. Anti-Cytokeratin 4 Antibody (1T236) can be used in WB.

Anti-Cytokeratin 4 Antibody (1T236)

Anti-Cytokeratin 4 Antibody (1T236)

Copy Product Info
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Catalog No. TMAB-04955
Anti-Cytokeratin 4 Antibody (1T236) is a Rabbit antibody targeting Cytokeratin 4. Anti-Cytokeratin 4 Antibody (1T236) can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Cytokeratin 4 Antibody (1T236) is a Rabbit antibody targeting Cytokeratin 4. Anti-Cytokeratin 4 Antibody (1T236) can be used in WB.
Ig Type
IgG
Clone
1T236
Reactivity
Rat (predicted:Human)
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with Cytokeratin 4 monoclonal antibody, unconjugated (TMAB-04955) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Tissue SpecificityDetected in the suprabasal layer of the stratified epithelium of the esophagus, exocervix, vagina, mouth and lingual mucosa, and in cells and cell clusters in the mucosa and serous gland ducts of the esophageal submucosa (at protein level). Expressed widely in the exocervix and esophageal epithelium, with lowest levels detected in the basal cell layer.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
Recombinant Protein: human Cytokeratin 4 protein (350-480aa)
Antigen Species
Human
Gene Name
KRT4
Gene ID
Protein Name
Keratin, type II cytoskeletal 4
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 57 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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