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Anti-CK10/Cytokeratin 10 Antibody (1G407)

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Catalog No. TMAB-04382

Anti-CK10/Cytokeratin 10 Antibody (1G407) is a Rabbit antibody targeting CK10/Cytokeratin 10. Anti-CK10/Cytokeratin 10 Antibody (1G407) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-CK10/Cytokeratin 10 Antibody (1G407)

Anti-CK10/Cytokeratin 10 Antibody (1G407)

😃Good
Catalog No. TMAB-04382
Anti-CK10/Cytokeratin 10 Antibody (1G407) is a Rabbit antibody targeting CK10/Cytokeratin 10. Anti-CK10/Cytokeratin 10 Antibody (1G407) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CK10/Cytokeratin 10 Antibody (1G407) is a Rabbit antibody targeting CK10/Cytokeratin 10. Anti-CK10/Cytokeratin 10 Antibody (1G407) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
1G407
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-10000; IHC-P: 1:1000-5000; IHC-Fr: 1:1000-5000; IF: 1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificitySeen in all suprabasal cell layers including stratum corneum.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCytokeratin 10 is a heterotetramer of two type I and two type II keratins. Cytokeratin 10 is generally associated with keratin 1. It is seen in all suprabasal cell layers including stratum corneum. A number of alleles are known that mainly differ in the Gly-rich region (positions 490-560). Defects in cytokeratin 10 are a cause of epidermolytic hyperkeratosis (EHK), also known as bullous congenital ichthyosiform erythroderma (BCIE) or bullous erythroderma ichthyosiformis congenita of Brocq. EHK is an hereditary skin disorder characterized by blistering and a marked thickening of the stratum corneum. At birth, affected individuals usually present with redness, blisters and superficial erosions due to cytolysis. Within a few weeks, the erythroderma and blister formation diminish and hyperkeratoses develop. Transmission is autosomal dominant, but most cases are sporadic. Defects in cytokeratin 10 are also a cause of annular epidermolytic ichthyosis (AEI), also known as cyclic ichthyosis with epidermolytic hyperkeratosis. AEI resembles clinical and histologic features of both epidermolytic hyperkeratosis and ichthyosis bullosa of Siemens.
Antigen Details
Immunogen
A synthesized peptide: human Cytokeratin 10
Antigen Species
Human
Gene Name
KRT10
Gene ID
Protein Name
Keratin, type I cytoskeletal 10
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 59 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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