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Synonyms: UNQ690/PRO1335, CAXiV


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | Carbonic Anhydrase 14 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q9ULX7. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc (IgG1) |
| Accession Number | Q9ULX7 |
| Construction | Ala16-Met290 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE |
| Endotoxin | < 0.1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 150 mM NaCl (pH 7.5). |
| Synonyms | UNQ690/PRO1335, CAXiV |
| Research Background | Carbonic anhydrase XIV (CA XIV), a transmembrane protein, highly expressed in the central nervous system, is difficult to recombinantly express and purify in large scale for the measurements of inhibitor binding and drug design. CA XIV belongs to the family of twelve catalytically active CA isoforms in the human body. Disorders in the expression of CA XIV cause serious diseases and CA XIV has been described as a possible drug target for the treatment of epilepsy, some retinopathies, and skin tumors. |
| Molecular Weight | 56.76 kDa (Predicted); 65-85 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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