IL-1 beta/IL-1F2 Protein , Human, Recombinant V2

Name: IL-1 beta/IL-1F2 Protein , Human, Recombinant V2
Brand: TargetMol
SKU: TMPY-01049U
Rating: 4.5 (1 reviews)

(Synonyms: interleukin 1, β, interleukin 1, beta, IL1-β, IL1F2, IL1-BETA, IL-1B, IL-1 β, IL-1 beta, IL-1) Copy Product Info

Synonyms: interleukin 1, β, interleukin 1, beta, IL1-β, IL1F2, IL1-BETA, IL-1B, IL-1 β, IL-1 beta, IL-1

Catalog No. TMPY-01049U Copy Product Info

IL-1 beta/IL-1F2 Protein , Human, Recombinant V2 is expressed in E. coli. The accession number is P01584.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$108	7-10 days	7-10 days
20 µg	$177	7-10 days	7-10 days
50 µg	$318	7-10 days	7-10 days
100 µg	$498	7-10 days	7-10 days
200 µg	$821	7-10 days	7-10 days
500 µg	$1,590	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Measured by its ability to induce NF-kB signaling in 293-IL1 Res cells. The ED50 for this effect is 20-100 pg/ml.
Description	IL-1 beta/IL-1F2 Protein , Human, Recombinant V2 is expressed in E. coli. The accession number is P01584.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	P01584
Construction	Ala117-Ser269
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 0.01 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 7.5.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	interleukin 1, β, interleukin 1, beta, IL1-β, IL1F2, IL1-BETA, IL-1B, IL-1 β, IL-1 beta, IL-1
Research Background	IL1B belongs to the IL-1 family. Interleukin 1 (IL-1) is a family of polypeptide cytokines consisting of two agonists, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2) encoded by two distinct genes and perform identical biological functions. IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response. It is identified as endogenous pyrogens, and is reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Chemical Properties

Molecular Weight

17.5 kDa (Predicted); 17 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.