store at low temperature
store at -80°C
Andecaliximab is a recombinant IgG4 monoclonal antibody targeting matrix metalloproteinase 9 (MMP9). Andecaliximab showed antifibrotic effects in a mouse model of idiopathic pulmonary fibrosis. Andecaliximab can be used to study gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF), as well as dengue virus.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 247.00 | |
5 mg | In stock | $ 647.00 | |
10 mg | In stock | $ 987.00 |
Description | Andecaliximab is a recombinant IgG4 monoclonal antibody targeting matrix metalloproteinase 9 (MMP9). Andecaliximab showed antifibrotic effects in a mouse model of idiopathic pulmonary fibrosis. Andecaliximab can be used to study gastric adenocarcinoma and idiopathic pulmonary fibrosis (IPF), as well as dengue virus. |
In vitro |
Andecaliximab increases serum IL-7 levels [ 1 ]. Andecaliximab ( 50 μg / mL ; 24 h ) reduced the phosphorylation of SMAD2 ( pSMAD2 ) in ABC cell lines [ 2 ]. |
In vivo |
Improving the diversity of T cell receptor (TCR) in tumor-infiltrating T cells, andecaliximab[1]. In a human NSG mouse model of idiopathic pulmonary fibrosis, andecaliximab (20 mg/kg; intraperitoneal injection, single) exhibited an anti-fibrosis effect[2]. |
Synonyms | GS-5745 |
Molecular Weight | N/A |
CAS No. | 1518996-49-0 |
store at low temperature
store at -80°C
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Andecaliximab 1518996-49-0 Microbiology/Virology Proteases/Proteasome Virus Protease MMP GS 5745 GS-5745 GS5745 inhibitor inhibit